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Title: Efficient synthesis of 9-aryl-6-(2-fluorophenyl)-1,2,4-triazolo[4,3- ] [1,8]naphthyridines using chloramine-T under microwave irradiation
Authors: Mogilaiah, K
Dhanaja, K
Srivani, N
Chandra, A Vinay
Keywords: 1,2,4-Triazole,1,8-naphthyridine;chloramine-T;micro¬wave irradiation
Issue Date: Apr-2010
Publisher: CSIR
Abstract: A simple and highly efficient procedure has been described for the synthesis of 9-aryl-6-(2-fluorophenyl)-1,2,4-triazolo[4,3- ][1,8]naphthyridines 8 by oxidation of the corresponding aryl aldehyde 3-(2-fluorophenyl)-1,8-naphthyridin-2-ylhydrazones 7 with chloramines-T in ethanol under microwave irradiation. The products are obtained in good yields and in state of high purity. The structures of the compounds 3-8 have been established on the basis of spectral (IR, 1H NMR and MS) and analytical data.
Page(s): 500-504
Appears in Collections:IJC-B Vol.49B(04) [April 2010]

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