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Title: Claisen-Schmidt condensation under solvent-free conditions
Authors: Mogilaiah, K
Swamy, T Kumara
Chandra, A Vinay
Srivani, N
Vidya, K
Keywords: Claisen-Schmidt condensation;1,8-naphthyridine;α-β-unsaturated ketones;solid NaOH;solvent-free conditions
Issue Date: Mar-2010
Publisher: CSIR
Abstract: Claisen-Schmidt condensation of 2-(4-acetyl-phenylamino)-3-(4-chlorophenyl)-1,8-naphthyridine 3 with various aromatic aldehydes under solvent-free conditions to prepare α-β-unsaturated ketones 4 using solid NaOH as catalyst has been described. The reaction proceeds efficiently at room temperature in high yields and in a state of excellent purity.
Page(s): 382-385
Appears in Collections:IJC-B Vol.49B(03) [March 2010]

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