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http://nopr.niscpr.res.in/handle/123456789/6630| Title: | Synthesis and antibacterial activity of 1,3,4-oxadiazolyl-1,8-naphthyridines |
| Authors: | Mogilaiah, K Vidya, K |
| Keywords: | 1,8-Naphthyridinyl acetic acid hydrazide;acetophenones;condensation;1,8-naphthyridinyl methylcarbonyl hydrazones acetic anhydride;cyclization;1,3,4-oxadiazolyl-1, 8-naphthyridines |
| Issue Date: | Aug-2006 |
| Publisher: | CSIR |
| IPC Code: | Int. Cl.8 C07D |
| Abstract: | Condensation of (2-oxo-3-phenyl-2H-[1,8]naphthyridin-1-yl)-acetic acid hydrazide 2 with different acetophenones yields the corresponding acetophenone (2-oxo-3-phenyl-2H-[1,8]naphthyridin-1-yl)methylcarbonyl hydrazones 3, which on treatment with acetic anhydride affords the respective 1-(4-acetyl-5-aryl-5-methyl-[1,3,4]oxadiazol-2-ylmethyl)-3-phenyl-1H-[1,8]naphthyridin-2-ones 4. The structures of the compounds 3 and 4 have been confirmed on the basis of analytical and spectral data. The compounds 4 have been screened for their antibacterial activity. |
| Page(s): | 1905-1908 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.45B(08) [August 2006] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(8) 1905-1908.pdf | 42.11 kB | Adobe PDF | View/Open |
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