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dc.contributor.authorPrasoona, G-
dc.contributor.authorKishore, B-
dc.contributor.authorBrahmeshwari, G-
dc.identifier.issn2583-1321 (Online); 0019-5103 (Print)-
dc.description.abstractSynthesis of novel benzo [4',5'] imidazo [1',2':1,2] pyrrolo [3,4-b] isoxazolo [4,5-e] pyridines 8 has been achieved by reaction of 1-(prop-2-yn-1-yl)-1H-benzo [d] imidazo-2-carbaldehydes 5 with 5-amino -3-methylisoxazole 6 in presence of InCl3 in CH3CN media, followed by reaction of imine 7 with BF3.Et2O in DCE at 80°C. The newly synthesized title compounds 8 have been evaluated for their in vitro antimicrobial activity. Compounds 8 exhibit potent antimicrobial activity compared to that of standard drugs.en_US
dc.publisherNIScPR-CSIR, Indiaen_US
dc.sourceIJC Vol.61(02) [February 2022]en_US
dc.subjectintramolecular Povarov reactionen_US
dc.subjectbenzo[4',5']imidazo[1',2':1,2]pyrrolo[3,4-b]isoxazolo[4,5-e] pyridinesen_US
dc.subjectantimicrobial activityen_US
dc.titleSynthesis and antimicrobial activity of novel benzo[4', 5']-imidazo[1',2':1,2]pyrrolo[3,4-b]isoxazolo[4,5-e]pyridinesen_US
Appears in Collections:IJC Vol.61(02) [February 2022]

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