Please use this identifier to cite or link to this item:
|Title:||Spiro-heterocycles: A convenient synthesis and antimicrobial activity of some 3-(5-aryl/aryloxymethyl-1,3,4-thiadiazol-2-yl)-spiro-cyclohexane-1',2-thiazolidin-4-ones|
|Keywords:||Substituted aryl/aryloxymethyl;1,3,4-thiadiazole;spiro-cyclohexane;antimicrobial activity;antifungal activity|
|Abstract:||A new series of novel 3-(5-aryl/aryloxy methyl-1,3,4-thiadiazol-2-yl)-spiro-cyclohexane-1'2-thiazolidin-4-ones have been synthesized from a common intermediate, in good yields. These compounds have been screened for their antibacterial and antifungal activity against different pathogenic strains of bacteria and fungi. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) have been determined for the test compounds as well as for reference standards. Compounds 3c, 3d, 6c and 6d have shown good antibacterial activity where as compounds 3a, 3b, 6a and 6b have displayed better antifungal activity.|
|Appears in Collections:||IJC-B Vol.60B(11) [November 2021]|
Files in This Item:
|IJC (Section B), 60B, 1490-1495 (Nov,2021).pdf||726.43 kB||Adobe PDF||View/Open|
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.