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http://nopr.niscpr.res.in/handle/123456789/5636| Title: | In vitro antifungal activity of Cassia alata Linn. flower extract |
| Authors: | Abubacker, M N Ramanathan, R Kumar, T Senthil |
| Keywords: | Antifungal activity;Cassia alata;Aflatoxin;Ringworm Senna;Plant pathogenic fungi;Human pathogenic fungi |
| Issue Date: | Feb-2008 |
| Publisher: | CSIR |
| IPC Code: | Int. cl.8— A61K 36/00, A61K 36/482, A61P 31/10 |
| Abstract: | The aqueous flower extract of Cassia alata Linn. (Family-Caesalpiniaceae) was investigated for antifungal activity by agar diffusion method against three distinct groups of fungi, viz. aflatoxin producing fungi, Aspergillus flavus (NCBT 101) and A. parasiticus (NCBT 128); plant pathogenic fungi, Fusarium oxysporum ( NCBT 156 ) and Helminthosporium oryzae (NCBT 165); and human pathogenic fungi Candida albicans (NCBT 140) and Microsporum audouinni (NCBT 173). Total inhibition (100%) of growth was seen at 10 and 15 mg/ml concentrations for aflatoxin producing fungal strains. Whereas for plant and human pathogenic fungi total inhibition was at 15mg/ml concentration. The minimum inhibitory concentration (MIC) values of the extract varied from 5.75 to 8.00mg/ml for these fungi. Thus, aqueous flower extract of C. alata can be used as a potential antifungal agent for these three varied groups of fungi. |
| Page(s): | 6-9 |
| ISSN: | 0975-1092 (Online); 0972-592X (Print) |
| Appears in Collections: | NPR Vol.7(1) [January-February 2008] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| NPR 7(1) 6-9.pdf | 69.62 kB | Adobe PDF | View/Open |
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