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Title: A simple and efficient one-pot synthesis of novel benzimidazo[1,2-a]- chromeno[4,3-d] pyrimidinones catalyzed by [Et3NH][HSO4]
Authors: Prasoona, G
Kishore, B
Brahmeshwari, G
Keywords: Multi-component synthesis;Benzimidazo[1,2-a]chromeno[4,3-d]pyrimidinones;Polyheterocycles;Triethyl ammonium hydrogen sulphate [TEAHS];Solvent-free conditions
Issue Date: Sep-2020
Publisher: NISCAIR-CSIR, India
Abstract: A simple and efficient one-pot synthesis of novel polyheterocyclic benzimidazo[1,2-a]- chromeno[4,3-d]pyrimidinones 4 via a three-component condensation of 2-aminobenzimidazole 1, aromatic aldehydes 2 and 4-hydroxy coumarin 3 catalyzed by Bronsted acid ionic liquid triethyl ammonium hydrogen sulphate [Et3NH][HSO4] under solvent-free conditions is reported. The main advantages of this protocol are short reaction time, easy work-up, operational simplicity, and excellent yields with high purity, without intervention of chromatography.
Page(s): 1418-1424
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.59B(09) [September 2020]

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