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http://nopr.niscpr.res.in/handle/123456789/55013| Title: | Condensation of nicotinaldehydes with acetophenones and NH4OAc: A convenient synthesis and biological activities of 2',6'-diphenyl-3,4'-bipyridines # |
| Authors: | Begum, Shahnaz Rajeswari, B Uma Zehra, A Tiwari, A K Prakasham, R S Raju, B China |
| Keywords: | Nicotinaldehydes;2',6'-diphenyl-3,4'-bipyridines;Anti-microbial activity;α-glucosidase inhibitory activity |
| Issue Date: | Jul-2020 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | 2',6'-Diphenyl-3,4'-bipyridines 3a-t have been achieved by the three-component, one-pot reaction of nicotinaldehydes 1a-b, acetophenones 2a-j and anhydrous ammonium acetate under solvent free conditions at 120°C. All the prepared compounds 3a-t have been screened for anti-microbial, free-radical scavenging and α-glucosidase inhibitory activities. Compounds 3m-r have shown anti-bacterial activity and compounds 3m-n identified as anti-fungal agents. Compounds 3d, 3h, 3m and 3r-s have shown α-glucosidase inhibitory activity. |
| Page(s): | 1001-1009 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.59B(07) [July 2020] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 59B(7) 1001-1009.pdf | Main Article | 204.42 kB | Adobe PDF | View/Open |
| IJCB 59B(7) 1001-1009_Suppl Data.pdf | Supplementary Data | 1.76 MB | Adobe PDF | View/Open |
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