Synthesis of some 3-(2-substituted sulfanyl-imidazo [2,1-b][1,3,4] thiadiazol-6-yl)-chromen-2-one and its derivatives

Abstract

A series of 3-(2-substituted sulfanyl-imidazo [2,1-b][1,3,4] thiadiazol-6-yl)-chromen-2-ones (<strong>3</strong>) have been synthesized from 3-(2-bromo acetyl) chromen-2-ones <strong>1</strong> and 2-amino-5-thio substituted[1,3,4]thiadiazole <strong>2 </strong>in anhydrous ethanol. The 7,8-benzo analogs of 3-(2-substituted sulfanyl-imidazo[2,1-<em>b</em>][1,3,4] thiadiazol-6-yl)-chromen-2-ones <strong>5</strong> have been synthesized under similar conditions. All the synthesized compounds have been characteriszed by analytical and spectral data.