Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/48783| Title: | Cytotoxic Activities of Different Solvent Extracts of Tirmania nivea and Terfezia claveryi against HepG2 and L929 Cells |
| Authors: | Elsayed, E A Alsahli, F D Enshasy, H A El Wadaan, M A |
| Keywords: | Truffles;Biological activity;Cytotoxic;HepG-2;L929 |
| Issue Date: | Jul-2019 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Desert truffles constitute an unexplored source for naturally occurring bioactive compounds. In the current work, different solvents have been used to extract bioactive components from T. nivea and T. claveryi. All tested extracts showed cytotoxic activities against HepG2 and L929 cells in a dose-dependent manner. Hexane extracts of T. nivea and T. claveryi gave highest toxicities of 91.23±0.03 and 92.7±0.01%, respectively, at 1 mg/mL, while the ethyl acetate extract resulted in toxicity of 94.5±0.02at 1 mg/mL in case of T. claveryi, which is higher by about 6% than that obtained for T. nivea. Furthermore, morphological examination showed that cells are gradually affected by increasing extract concentration. |
| Page(s): | 454-457 |
| ISSN: | 0975-1084 (Online); 0022-4456 (Print) |
| Appears in Collections: | JSIR Vol.78(07) [July 2019] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| JSIR 78(7) 454-457.pdf | 337 kB | Adobe PDF | View/Open |
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