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dc.contributor.authorDesai, N C-
dc.contributor.authorBhatt, N B-
dc.contributor.authorJoshi, Surbhi B-
dc.identifier.issn0975-0983(Online); 0376-4699(Print)-
dc.description.abstractA highly efficient method for the synthesis of 1-((1-(4-(2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)ethylidene)amino)-6-((arylidene)amino)-4-(3-nitrophenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitriles is described. The structures have been confirmed by IR, 1H and 13C NMR, and mass spectral techniques. The synthesized compounds have been tested for antimicrobial activity. The title compounds 4a-o have been studied against strains of bacteria (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pyogenes) and fungi (Candida albicans, Aspergillus niger and Aspergillus clavatus) by serial dilution method. Compounds 4b (-2-OH), 4f (-4-NO2), 4h (-3-Cl), 4j (-4-OCH3), 4l (-4-OH-3-OCH3) and 4m (-N,N’-(CH3)2) exhibit good in vitro antimicrobial activity.en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJC-B Vol.58B(04) [April 2019]en_US
dc.subjectAntibacterial activityen_US
dc.subjectAntifungal activityen_US
dc.subjectSAR studyen_US
dc.titleSynthesis and antimicrobial importance of oxazine bearing pyridine scaffolden_US
Appears in Collections:IJC-B Vol.58B(04) [April 2019]

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