Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/4567
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dc.contributor.authorMedhi, B-
dc.contributor.authorPrakash, A-
dc.contributor.authorAvti, P K-
dc.contributor.authorSaikia, U N-
dc.contributor.authorPandhi, P-
dc.contributor.authorKhanduja, K L-
dc.date.accessioned2009-06-15T11:45:45Z-
dc.date.available2009-06-15T11:45:45Z-
dc.date.issued2008-08-
dc.identifier.issn0975-1009 (Online); 0019-5189 (Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/4567-
dc.description583-590en_US
dc.description.abstractManuka honey (MH, 5g/kg) provided protection against trinitro-benzo-sulphonic acid induced colonic damage. Combination therapy (MH+sulfasalazine) also reduced colonic inflammation and all the biochemical parameters were significant compared to control and MH alone treated group. Combination therapy showed additive effect of the MH which restored lipid peroxidation and improvement of antioxidant parameters. Morphological and histological scores were significantly reduced in combination groups. In inflammatory model of colitis, oral administration of MH (5g/kg) and combination with sulfasalazine (360 mg/kg) with MH (5g/kg) significantly reduced the colonic inflammation. The results indicate the additive effect of Manuka honey with sulfasalazine in colitis.en_US
dc.language.isoen_USen_US
dc.publisherCSIRen_US
dc.sourceIJEB Vol.46(08) [August 2008]en_US
dc.subjectAntioxidant defense systemen_US
dc.subjectMonuka honeyen_US
dc.subjectSulfasalazineen_US
dc.subjectUlcerative colitisen_US
dc.titleEffect of Manuka honey and sulfasalazine in combination to promote antioxidant defense system in experimentally induced ulcerative colitis model in ratsen_US
dc.typeArticleen_US
Appears in Collections:IJEB Vol.46(08) [August 2008]

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