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Title: Green synthesis of pyrazolo[4,3-d]isoxazol derivatives and their antimicrobial, antimalarial and antituberculosis evaluation
Authors: Vekariya, Rajesh H
Patel, Kinjal D
Vekariya, Mayur K
Prajapati, Neelam P
Rajani, Dhanji P
Rajani, Smita D
Patel, Hitesh D
Keywords: Pyrazolo[4,3-d]isoxazol;Isoxazol-5(4H)-ones;Green synthesis;Antimicrobial;Antimalarial;Antituberculosis
Issue Date: Aug-2018
Publisher: NISCAIR-CSIR, India
Abstract: This article deals with the synthesis of new pyrazolo[4,3-d]isoxazol derivatives by utilizing 3,4-disubstituted isoxazol-5(4H)-ones and thiosemicarbazide catalyzed by triethylamine in PEG-400 under MWI at 300 W as well as under thermal heating at 90°C. All the synthesized compounds have been characterized by various spectroscopic techniques such as 1H and 13C NMR, IR, ESI-MS and elemental analysis. All the synthesized compounds have been screened for antimicrobial, antimalarial and antituberculosis activities.
Page(s): 1033-1041
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.57B(08) [August 2018]

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