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Title: Synthesis and antimicrobial activity of naphtho-[1,2-e][1,3]oxazines linked benzimidazole
Authors: Kishore, B
Prasoona, G
Brahmeshwari, G
Keywords: 2-(1H-Benzo[d]imidazol-2-yl)-2,3-dihydro-1-aryl-1H-naphtho[1,2-e][1,3]oxazines;One-pot synthesis;Three- component reaction;Antimicrobial activity
Issue Date: Nov-2017
Publisher: NISCAIR-CSIR, India
Abstract: A new series of 2-(1H-benzo[d]imidazol-2-yl)-2,3-dihydro-1-aryl-1H-naphtho-[1,2-e][1,3]oxazines have been accomplished by a green protocol utilizing an efficient atom economic three component coupling reaction. The reaction of 2-amino benzimidazole, aromatic aldehydes with β-naphthol on oil bath has produced the corresponding 1-(1H-benzo[d]imidazol-2-yl amino) phenyl (methyl) naphthalene-2-ols, which have been then cyclized to the title products by treatment with formaldehyde. The title compounds have been screened for their antimicrobial activity. Some of the compounds show promising antimicrobial activity.
Page(s): 1185-1192
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.56B(11) [November 2017]

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