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Title: In vitro anti-inflammatory activity of a new allelochemical from the bark of Pithecellobium dulce (Roxb.) Benth.
Authors: Yadava, R N
Chakravarty, Archana
Keywords: Pithecellobium dulce (Roxb.) Benth;Leguminosae;Bark;Allelochemicals (plant secondary metabolites);Anti-inflammatory activity
Issue Date: Apr-2017
Publisher: NISCAIR-CSIR, India
Abstract: Pithecellobium dulce (Roxb.) Benth. belongs to family Leguminosae which is commonly known as Vilayati imli or Jangle Jalebi in Hindi. It is a native of tropical America and cultivated throughout India. Its bark is reported to be used as astringent in dysentery and as febrifuge. It is also used in dermatitis and eye inflammation. A new allelochemical has been isolated from methanolic extract of the bark of this plant, along with two known compounds sinenestin (B), apigenin-7-O-glucopyranoside (C). The structure of a new allelochemical (A) has been characterized as 3,5,7,3′,4′-pentahydroxy flavone-7-O-α-L-rhamnopyranosyl-3′-O-β-D-xylopyranosyl (1→3)–O-β-D-glucopyranoside, by various colour reactions, chemical degradations and spectroscopic analysis. In vitro anti-inflammatory assay of compound A shows significant anti-inflammatory activity against the denaturation of egg albumin protein.
Page(s): 447-452
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.56B(04) [April 2017]

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