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http://nopr.niscpr.res.in/handle/123456789/41185| Title: | Synthesis and characterization of thiazole anchored fluorinated 2-heterylchromones and pyrazoles |
| Authors: | Akolkar, H N Randhavane, P V Karale, B K |
| Keywords: | Hydroxyacetophenone;β-diketone;Baker-Venkataraman transformation;Heterylchromones;Pyrazoles |
| Issue Date: | Apr-2017 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Esterification of 2-(4-fluorophenyl)-4-methylthiazole-5-carboxylic acid 4 with 2-hydroxyacetophenones 5 yields compounds 6 which have been converted to β-diketones 7 by Baker-Venkataraman transformation. A series of 2-substituted chromones 8 have been obtained by acid catalysed intramolecular cyclization of β-diketones. Substituted pyrazoles 9 have been obtained from β-diketones 7. Formation of all the synthesized compounds have been confirmed by the spectroscopic techniques. |
| Page(s): | 458-462 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.56B(04) [April 2017] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 56B(4) 458-462.pdf | 74.09 kB | Adobe PDF | View/Open |
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