Microwave assisted synthesis of some novel class of bisisoxazoline derivatives and their further applications

Abstract

Synthesis of some new bisisoxazoline derivatives have been described from terepthaldehyde derived bisnitrones using microwave irradiation via 1,3-dipolar cycloaddition reaction. Bisisoxazoline derivatives have been in turn successfully converted into new bisaziridine derivatives via Baldwin rearrangement. Simple reaction methodology, greener approaches, non involvent of catalysts, good to excellent yields are the important features highlighted in this synthesis.