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Title: Impact of organophosphate pesticides, methyl parathion and chlorpyrifos on some tissue enzymes in fish (Aphanius dispar)
Authors: Shoaib, Nafisa
Siddiqui, Pirzada Jamal Ahmed
Keywords: Pesticides;Methyl parathion;Chlorpyrifos;Alanine aminotransferase;Acetyl cholinesterase;Lactate dehydrogenase
Issue Date: Jul-2016
Publisher: NISCAIR-CSIR, India
Abstract: In the present study acute effects of methyl parathion and chlorpyrifos on tissue enzyme activity (acetyl cholinesterase (AChE), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), acid phosphatase (ACP) and alkaline phosphatase (ALP) were assessed in fish juveniles using enzyme analysis kit. Results depict both elevation and inhibition of enzymes in the treated fish. The results revealed significant elevation in ALT activity of both pesticide i.e., methyl parathion and chlorpyrifos by (105%) and (118%) as compared to control and inhibition in AChE, LDH, AST and ALP enzymes. The AChE and ALP activity levels decreased significantly (p< 0.05) in both pesticide treated groups. Significant decrease levels of ACP activity in fish tissue were noticed in methyl parathion treated fish. But in case of chlorpyrifos treated fish, increase in ACP activity (101%) was observed, however the increase was not significant (p< 0.05).
Page(s): 869-874
ISSN: 0975-1033 (Online); 0379-5136 (Print)
Appears in Collections:IJMS Vol.45(07) [July 2016]

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