Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/34217| Title: | An efficient synthesis of novel carbohydrate and thiosemicarbazone hybrid benzimidazole derivatives and their antimicrobial evaluation |
| Authors: | Panchal, Shyamali N Vekariya, Rajesh H Patel, Kinjal D Prajapati, Shraddha M Rajani, Dhanji P Rajani, Smita D Patel, Hitesh D |
| Keywords: | Antibacterial activity;Antifungal activity;Benzimidazole;Thiosemicarbazone;Carbohydrate;Microwave irradiation |
| Issue Date: | May-2016 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A library of thiosemicarbazide hybrid 2-(aldo-polyhydroxyalkyl)benzimidazole derivatives have been designed and synthesized with simple and eco-friendly methodologies. The structures of the compounds have been elucidated with the aid of elemental analysis, IR, mass and 1H NMR spectral data. These novel synthesized compounds have been evaluated for their antibacterial activity against two gram-positive bacteria (S. aureus and S. pyogenus) and two gram-negative bacteria (P. aeruginosa and E. coli). The title compounds have also been studied for their antifungal activity against C. albicans, A. niger and A. clavatus using the broth dilution technique. |
| Page(s): | 604-612 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.55B(05) [May 2016] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 55B(5) 604-612.pdf | 175.46 kB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.