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http://nopr.niscpr.res.in/handle/123456789/33638| Title: | A new embelin from the mangrove Aegiceras corniculatum |
| Authors: | Thota, Satya Prakasa Rao Sarma, Nittala S Murthy, Y L N |
| Keywords: | Aegiceras corniculatum;Quinonoids;Antimalarial activity |
| Issue Date: | Jan-2016 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | One new compound (2) and five known compounds (1, 3-6) have been isolated from the mangrove plant Aegiceras corniculatum collected from the Godavari mangrove forest, India. The structure of the new compound has been established by 1H and 13C NMR spectroscopy and mass spectral data as 2,5-didehydroxy-6-methylembelin (2). The known compounds have been characterized as 4-hydroxy-2-methoxybenzamide (1), embelin (3), 5-O-ethylembelin (4), 5-O-methylembelin (5) and 4-methoxyresorcinol (6). Compounds 2-5 exhibit moderate antimalarial activity. Embelin (3) shows activity against chloroquine-resistant strains better than against chloroquine-sensitive strains of Plasmodium falciparum. |
| Page(s): | 123-127 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.55B(01) [January 2016] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 55B(1) 123-127.pdf | 151.7 kB | Adobe PDF | View/Open |
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