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Title: Antibacterial, antioxidant and phytochemical properties of the ethanolic extract of Ocimum obovatum E.Mey. ex Benth.
Authors: Naidoo, Y
Sadashiva, C T
Naidoo, G
Raghu, K
Keywords: Ocimum obovatum E.Mey. ex Benth.;Antibacterial;Antioxidant;Phytochemical;South Africa
Issue Date: Jan-2016
Publisher: NISCAIR-CSIR, India
IPC Code: Int. Cl.8: A61K 36/00, C09K 15/00, C12M, C12N, C01, C07, C08
Abstract: This study evaluated the potential antibacterial, antioxidant and phytochemical properties of the ethanolic extract of the leaves of Ocimum obovatum E.Mey. ex Benth. The ethanolic extract of O. obovatum was tested in vitro against Gram-positive (Staphylococcus aureus, Klebsiella sp, and Escherichia coli) and Gram-negative (Proteus sp. and Pseudomonas sp.) strains of bacteria by the disc diffusion method. The maximum inhibition was against Staphylococcus aureus with an inhibition zone of 18 mm. The minimum inhibitory concentration of the extract against the bacteria was also determined. A standard antibiotic disc with Chloramphenicol was used as the positive control. The extract was further tested for antioxidant activity using the 2, 2-diphenyl-1-picryl hydrazyl radical (DPPH) method which was then compared with standard butylated hydroxyanisole (BHA). Antioxidant activity was IC50220±0.05µg/ml. Phytochemical screening of the leaves showed the presence of carbohydrates, phenols, flavonoids, tannins, saponins, fixed oils and fats, glycosides and terpenoids.
Page(s): 57-61
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.15(1) [January 2016]

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