<span style="font-size:13.0pt;mso-bidi-font-size:8.0pt;mso-bidi-language:HI" lang="EN-GB">Co(II), Ni(II), Cu(I) and Pd(II) complexes of <i style="mso-bidi-font-style:normal">p</i>-anisaldene-thiosemicarbazone </span>

Abstract

<span style="letter-spacing:-.1pt;mso-bidi-language: HI" lang="EN-GB">The reaction of anisaldene-thiosemicarbazone (HL) with MCl₂.6H₂O (where M = Co(II) and Ni(II) ), Cu(CH₃COO)₂.H₂O and [Pd(COD)Cl₂] on stirring/refluxing affords six-coordinated [Co(L)₂(HL)] (<b style="mso-bidi-font-weight:normal">1</b>) and four-coordinated [Ni(L)₂] (<b style="mso-bidi-font-weight:normal">2</b>), [Cu(L)(HL)] (<b style="mso-bidi-font-weight:normal">3</b>) and [Pd(L)(COD)]Cl (<b style="mso-bidi-font-weight:normal">4</b>) complexes. All the complexes have been characterized by conductivity measurements, FTIR, UV-vis, ESI(+) mass, ^{<span style="mso-bidi-font-style:italic">13</span>}C and ^{<span style="mso-bidi-font-style:italic">1</span>}H NMR spectroscopy, TGA-DTA analysis, magnetic and cyclic voltammetry studies and screened <i style="mso-bidi-font-style:normal">in vitro</i> for antimicrobial activity by the agar well method. The ligand and the Cu(I) complex have been tested for anticancer activity The Cu(I) complex exhibits quite good antifungal activity against <i style="mso-bidi-font-style:normal">R. solani</i> and <i style="mso-bidi-font-style:normal">F. oxosporum ciceri, </i>and also possesses better antiproliferative activity than the ligand against the cancer cells.

</span>