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Title: Studies on biochemical and biological properties of turrids venom (Turricula javana and Lophiotoma indica) [RETRACTED ARTICLE]
Authors: Arumugam, M
Giji, S
Tamilmozhi, S
Kumar, Sunil
Balasubramanian, T
Keywords: Turrids;Marine toxin;HPLC;HPTLC;Peptides;Pharmacology;Venom;Evolution
Issue Date: Oct-2013
Publisher: NISCAIR-CSIR, India
Abstract: Turritoxins were isolated from the venom ducts of Turrid snails Turricula javana and Lophiotoma indica collected from Parangipettai waters, south east coast of India. Venom duct yield 1 g/Kg was dissected from both the species. Crude venom exhibited protein concentration of 0.138mg/ml and 6mg/ml respectively. Venom containing toxicity was analyzed by SDS-PAGE and revealed their protein bands with an apparent molecular weight of 25 kDa, 41 kDa and 95 kDa for T. javana and 28 kDa and 66 kDa for L. indica. Many components with molecular mass ranging 29-97kDa exhibited prominent caseinolytic and gelatinolytic activities with prominent hemolytic acitivty upto the dilution of 10-6. The lethal concentration, LC50 was determined in Artemia salina. In addition, the quantitative status of free amino acids was performed through HPTLC. Presence of peptides was revealed by using HPLC, which was indicative of viable biological properties.
Page(s): 800-806
ISSN: 0975-1033 (Online); 0379-5136 (Print)
Appears in Collections:IJMS Vol.42(6) [October 2013]

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