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dc.contributor.authorGunasundari, V-
dc.contributor.authorKumar, T T Ajith-
dc.contributor.authorKumaresan, S-
dc.contributor.authorBalagurunathan, R-
dc.contributor.authorBalasubramanian, T-
dc.identifier.issn0975-1033 (Online); 0379-5136 (Print)-
dc.description.abstractPresent study is aimed to screen and isolate the antibiotic compounds from the mucus of Sea-anemone Heteractis magnifica. Mucus was extracted and characterized using gel chromatography, Reverse Phase High Performance Liquid Chromatography and spectroscopic methods. A molecular weight of purified protein was found to be 17KDa on SDS-PAGE. Protein content of mucus recorded was 0.62mg/ml - Mucus extract exhibited significant hemolytic activity in human, sheep, chicken and fish erythrocytes. Median lethal concentration was determined using Artemia nauplii. Antimicrobial activity screening was performed against the ten isolated bacterial pathogens and well inhibits the growth of Aeromonas hydrophila, Flavobacterium sp., Pseudomonas fluorescens, Micrococcus sp., and Streptococcus sp. The aliphatic nature of the mucus was determined by using FTIR spectroscopic analysis. This is the first report on the aliphatic-antibiotic compounds derived from Heteractis magnifica mucus which is used as marine ornamental fish disease controlling agent. en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJMS Vol.42(6) [October 2013]en_US
dc.subjectHeteractis magnificaen_US
dc.subjectArtemia naupliien_US
dc.subjectHemolytic activityen_US
dc.subjectFish pathogenen_US
dc.subjectAntimicrobial activityen_US
dc.titleIsolation of aliphatic-antibiotic compounds from marine invertebrate, Heteractis magnifica ʽQuoy & Gaimard, 1833ʼ against captive marine ornamental fish pathogens en_US
Appears in Collections:IJMS Vol.42(6) [October 2013]

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