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Title: | Synthetic and antibacterial studies of rhodanine derivatives with indol-2,3-diones |
Authors: | Pardasani, R T Pardasani, P Sherry, D Chaturvedi, V |
Issue Date: | Dec-2001 |
Publisher: | NISCAIR-CSIR, India |
Abstract: | A facile synthesis of new isatylidene and quinoline derivatives is described by treatment of rhodanine with indol-2,3-diones via Knoevenagel condensation and Pfitzinger reaction respectively. The reaction of indol-2,3-dione derivatives with five membered heterocycles, viz rhodanine under normal and basic conditions is described. While refluxing with ethanol it afford 3,4-dihydro-3-[2-thioxo-4 –thiazolidinone]indol-2-one 3, under basic conditions l-methyl-2-thio-4-thiazolidino[5,4-b] quinoline-4-carboxylic acid 4 is obtained. The compounds 3 and 4 have been characterized by spectral studies and elemental analyses and screened for antibacterial activity. |
Page(s): | 1275-1278 |
ISSN: | 0975-0983(Online); 0376-4699(Print) |
Appears in Collections: | IJC-B Vol.40B(12) December 2001] |
Files in This Item:
File | Description | Size | Format | |
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IJCB 40B(12) 1275-1278.pdf | 2.45 MB | Adobe PDF | View/Open |
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