Please use this identifier to cite or link to this item:
Title: Electromagnetic exposure effects the hippocampal dentate cell proliferation in gerbils (Meriones unguiculatus)
Authors: Hoffmann, K
Bagorda, F
Stevenson, A F G
Teuchert-Noodt, G
Issue Date: Dec-2001
Publisher: NISCAIR-CSIR, India
Abstract: The chronic effect on hippocampal neurogenesis after exposure (30 min/day for 14 days) to a high frequency (35,53 kHz) electromagnetic field, double modulated at extremely low frequencies (ELF; 1, 8, 12, 29 and 50 Hz), was studied in young adult gerbils. Immediately after the last exposure proliferation of dentate granule cells was identified by in vivo labeling with 5-bromo-2-desoxyuridine (BrdU). Exposure to 1, 29 and 50 Hz resulted in a statistically significant reduction of cell proliferation rates, but only the 50Hz-group manifested the effect highly significantly (-29,3 %). On the other hand, gerbils exposed to 8 and 12 Hz showed no significant change of postmitotic cell proliferation as compared with the sham treated controls. The results suggest that the effects of ELF on the granule cell proliferation are mediated by neurotmnsmitters and hormones which regulate hippocampal neurogenesis.
Page(s): 1220-1226
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.39(12) [December 2001]

Files in This Item:
File Description SizeFormat 
IJEB 39(12) 1220-1226.pdf1.44 MBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.