Please use this identifier to cite or link to this item:
Title: Exploitation of fermented shrimp-shells hydrolysate as functional food: Assessment of antioxidant, hypocholesterolemic and prebiotic activities
Authors: Halder, Suman Kumar
Adak, Atanu
Maity, Chiranjit
Jana, Arijit
Das, Arpan
Paul, Tanmay
Ghosh, Kuntal
Mohapatra, Pradeep Kumar Das
Pati, Bikas Ranjan
Mondal, Keshab Chandra
Keywords: Aeromonas hydrophila;Antioxidant;Functional food;Hypocholesterolemic;Oxidative stress;Shrimp-shells hydrolysate
Issue Date: Nov-2013
Publisher: NISCAIR-CSIR, India
Abstract: In the present study the bioactivities of chitooligosaccharides of fermented shrimp-shell hydrolysate (SSH) in respect to hypocholesterolemic, antioxidant and prebiotic activity were tested in male albino rat. Rats were treated with four different diets, viz., (i) cholesterol-rich (5%) basal diet (ChB), (ii) ChB+10% chitin, (iii) ChB+10% SSH and (iv) control group (without cholesterol). After 4 weeks of treatment, body mass index, liver weight, serum total cholesterol and LDL-cholesterol in groups (ii) and (iii) were decreased significantly than group (i). SSH supplementation significantly resists oxidative stress by reducing the thiobarbituric acid reactive substances and by increasing catalase, superoxide dismutase and free radical scavenging activity. The colonization of Lactobacillus and Bifidobacterium population in small and large intestine were more in group (iii) than other groups. Reduction of Clostridium perfringens population and non-significant changes of E. coli was also noted in SSH supplement group. Histological study revealed that the villus height and villus:crypt of the small intestine were increased significantly in SSH supplemented group (iii) without any diarrheal symptoms. The results demonstrated that the shrimp-shells hydrolysate has hypocholesterolemic effect, can resist lipid peroxidation and can influence the growth of health beneficial microbes, hence can be used as functional food for hypercholesterolemic patients.
Page(s): 924-934
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.51(11) [November 2013]

Files in This Item:
File Description SizeFormat 
IJEB 51(11) 924-934.pdf1.03 MBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.