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Title: Antiviral profile of Nyctanthes arbortristis L. against encephalitis causing viruses*
Authors: Gupta, P
Bajpai, S K
Chandra, K
Singh, K L
Tandon, J S
Keywords: Antiviral activity;Encephalitis causing viruses;Encephalomyocarditis virus (EMCV);Nyctanthes arbortristis;Semliki forest virus (SFV)
Issue Date: Dec-2005
Publisher: NISCAIR-CSIR, India
Abstract: The ethanolic extracts, various fractions and two pure compounds isolated from the plant N. arbortristis were tested against Encephalomyocarditis Virus (EMCV) and Semliki Forest Virus (SFV). Pronounced in vitro virus inhibitory activity was observed with the ethanolic and n-butanol fractions as well as with the pure compounds arbortristoside A and arbortristoside C. In addition, ethanolic extracts and n-butanol fraction protected EMCV infected mice to the extent of 40 and 60% respectively against SFV at a daily dose of 125 mg/kg body weight.
Page(s): 1156-1160
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.43(12) [December 2005]

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