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Title: | Chemical transformation of andrographolide† |
Authors: | Pal, Mahesh Singh, Meenakshi Sharma, R P |
Issue Date: | Sep-2002 |
Publisher: | NISCAIR-CSIR, India |
Abstract: | Tosylation of andrographolide 1, with p-TsCl pyridine furnishes compounds 3 and 4. The reaction of 1 with in situ generated nickel boride yields compounds 6 and 8. Monotosylation of 6 followed by reaction with NaI refluxing in acetone furnishes the iodide 13. But all attempts to generate an oxetane moiety in 13 corresponding to compund 2 failed. |
Page(s): | 1915-1918 |
ISSN: | 0975-0983(Online); 0376-4699(Print) |
Appears in Collections: | IJC-B Vol.41B(09) [September 2002] |
Files in This Item:
File | Description | Size | Format | |
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IJCB 41B(9) 1915-1918.pdf | 748.33 kB | Adobe PDF | View/Open |
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