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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Srivastava, Arun K | - |
dc.contributor.author | Shakeel, Mohd | - |
dc.contributor.author | Khan, Arbab A | - |
dc.date.accessioned | 2013-10-10T11:59:13Z | - |
dc.date.available | 2013-10-10T11:59:13Z | - |
dc.date.issued | 2002-02 | - |
dc.identifier.issn | 0975-0983(Online); 0376-4699(Print) | - |
dc.identifier.uri | http://hdl.handle.net/123456789/21845 | - |
dc.description | 436-439 | en_US |
dc.description.abstract | QSAR studies, using structural parameters such as equalized electronegativity 'Xeq', molecular connectivity ‘1b' and hydrophobicity ‘logP' on a novel series of ω-amino alkanoic acid derivatives of betulinic acid, have been discussed. Anti HIV-1 activity of these compounds both in CEM-4 and MT-4 cell cultures is found to correlate well with steric 1b as well as electronic Xeq parameters. The presence of an amide function is found to be important for activity. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | NISCAIR-CSIR, India | en_US |
dc.rights | CC Attribution-Noncommercial-No Derivative Works 2.5 India | en_US |
dc.source | IJC-B Vol.41B(02) [February 2002] | en_US |
dc.title | QSAR studies on anti HIV-1 N-substituted betulinic acid amides | en_US |
dc.type | Article | en_US |
Appears in Collections: | IJC-B Vol.41B(02) [February 2002] |
Files in This Item:
File | Description | Size | Format | |
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IJCB 41B(2) 436-439.pdf | 720.25 kB | Adobe PDF | View/Open |
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