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Title: | A new route for the convenient synthesis of 3-aminomethyl-3,5 ,5-trimethyl-cyclohexanol |
Authors: | Pandey, Satish C Singh, Sudhir S Patra, Balaram Ghosh, Anil C |
Issue Date: | Dec-2004 |
Publisher: | NISCAIR-CSIR, India |
IPC Code: | Int.Cl.7 C 07 C13/18,35/00 |
Abstract: | There has been a considerable chemical and biological interest in influenza fusion inhibitors namely, 3-aminomethyl-3,5,5-trimethyl-cyclohexanol 5. This compound has been identified as an important inhibitor of influenza virus fusion derivative and a potent and effective surrogate for the quinolizidine moiety. A new convenient route for the synthesis of 5 and for two new intermediates 1,3,3-trimelhyl-5-oxo-cyclohexane-carboxylic acid amide 3 and 5-hydroxy-1,3,3-trimethyl-cyclohexane-carboxylic acid amide 4. |
Page(s): | 2705-2707 |
ISSN: | 0975-0983(Online); 0376-4699(Print) |
Appears in Collections: | IJC-B Vol.43B(12) December 2004] |
Files in This Item:
File | Description | Size | Format | |
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IJCB 43B(12) 2705-2707.pdf | 589.95 kB | Adobe PDF | View/Open |
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