Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/19859| Title: | New Curcumin - Bioconjugate: Synthesis and DNA Binding |
| Authors: | Kumar, Sanjay Shukla, Vibha Misra, Arvind Tripathi, Snehlata Misra, Krishna |
| Keywords: | Curcumin;Glycine;Bioconjugate;Viscosity;Interaction;Groove binding |
| Issue Date: | Apr-2002 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A triglycyl derivative of curcumin, 1,7-bis (4-O-glycinoyl-3-methoxy phenyl)-1,6-heptadine-C-4-glycinoyl-3, 5-dione, was synthesized and characterized by UV, elemental analysis and 1H NMR. Interaction studies of curcumin and curcumin-bioconjugate with calf thymus DNA were carried out using UV -absorbance, gel electrophoresis and viscometric studies. Curcumin-bioconjugate was found to be A-T specific minOI- groove binder. |
| Page(s): | 158-163 |
| ISSN: | 0975-0967 (Online); 0972-5849 (Print) |
| Appears in Collections: | IJBT Vol.01(2) [April 2002] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJBT 1(2) 158-163.pdf | 1.42 MB | Adobe PDF | View/Open |
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