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http://nopr.niscpr.res.in/handle/123456789/19042| Title: | Inhibitory effect of piceatannol, a protein tyrosine kinase inhibitor, on asexual maturation of Plasmodium falciparum |
| Authors: | Mishra, Neerad C Sharma, Manju Sharma, Arun |
| Issue Date: | Apr-1999 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | This report describes the effect of piceatannol (3,4,3' ,5' -tetrahydroxy trans stilbene), a plant secondary natural product, on protein tyrosine kinase (PTK) activity in different stages of P. falciparum grown in vitro. Piceatannol inhibited PTK activity in trophozoites and schizonts suggesting that PTK may be important in the initial asexual maturation of the parasite. Inhibition of PTK activity by piceatannol may thus provide new insights into more specific tools for chemotherapeutic interventions for P. falciparum. |
| Page(s): | 418-420 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.37(04) [April 1999] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 37(4) 418-420.pdf | 683.43 kB | Adobe PDF | View/Open |
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