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dc.contributor.authorSharma, R K-
dc.contributor.authorChopra, Shilpa-
dc.contributor.authorKidwai, M-
dc.date.accessioned2013-05-31T09:51:45Z-
dc.date.available2013-05-31T09:51:45Z-
dc.date.issued2001-11-
dc.identifier.issn0975-0975(Online); 0376-4710(Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/18616-
dc.description1240-1242en_US
dc.description.abstractFormation constants of Cu, Ni , Co, Zn, Mn and Mg with 6-fluoro- 7 -(S-nonyl- I ,3,4-oxadiazol-2-y Isulphanyl)-4-quinolone-3- carboxylic acid have been determined using BEST program. Species distribution is plotted using programs BEST and SPE which indicates that at biological pH value, complex formation is taking place with Mg. Molecular mechanics calculations also confirm the complexation behaviour of the ligand . This supports the explanation of antibacterial mechanism through complexation of drug with Mg of bacterial DNA.en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJC-A Vol.40A(11) [November 2001]en_US
dc.titleFormation constants and molecular modelling studies on interaction of metal ions with 6- f1uoro-7-(5-nonyl-1 ,3,4-oxadiazol-2-ylsulphanyl)-4-quinolone-3-carboxylic acid [QDA]en_US
dc.typeArticleen_US
Appears in Collections:IJC-A Vol.40A(11) [November 2001]

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