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http://nopr.niscpr.res.in/handle/123456789/1757| Title: | Cu(OTf)₂ catalyzed Biginelli type condensation of aldehydes, β-keto esters and carbamates: Synthesis of 3,4-dihydro[1,3]oxazin-2-ones |
| Authors: | Jagdale, Arun R Paraskar, Abhimanyu S Sudalai, Arumugam |
| Keywords: | Aldehydes;Catalysts;Multicomponent reaction;Copper |
| Issue Date: | Jul-2008 |
| Publisher: | CSIR |
| Abstract: | Cu(OTf)₂ catalyzes effectively a new multicomponent reaction comprising aldehydes, β-ketoester and methyl carbamate in acetonitrile to afford substituted 3,4-dihydro[1,3]oxazin-2-ones in 60-82% yields. These compounds have been found to show inhibition activity against HL-60 cancer cell. |
| Page(s): | 1091-1095 |
| ISSN: | 0376-4699 |
| Appears in Collections: | IJC-B Vol.47B(07) [July 2008] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 47B(7) 1091-1095.pdf | 186.4 kB | Adobe PDF | View/Open |
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