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Title: Hepatoprotective activity of Eurycoma longifolia Jack. roots
Authors: Panjaitan, Ruqiah ganda putri
Handharyani, Ekowati
Manalu, Wasmen
Keywords: Eurycoma longifolia Jack;Therapeutic dose;Hepatoprotective
Issue Date: Apr-2013
Publisher: NISCAIR-CSIR, India
IPC Code: Int. Cl.8: A61K 36/00, A01D 7/54
Abstract: The hepatoprotective activity of Eurycoma longifolia Jack. roots methanol-water fraction on therapeutic dose was evaluated in carbon tetrachloride (CCl4)-induced rats. Hepatic cells were still normal after three months administration of methanol-water fraction at therapeutic dose. The administration of methanol-water fraction on therapeutic dose prior to CCl4-induced or CCl4-induced prior to methanol-water fraction resulted in suppression of ALT and AST. Histopathological and ultrastructure studies confirmed that methanol-water fraction protected hepatic cells. It is concluded that the methanol-water fraction of pasak bumi roots has a hepatoprotective activity.
Page(s): 225-230
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.12(2) [April 2013]

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