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http://nopr.niscpr.res.in/handle/123456789/16865| Title: | Hepatoprotective activity of Eurycoma longifolia Jack. roots |
| Authors: | Panjaitan, Ruqiah ganda putri Handharyani, Ekowati Chairul Manalu, Wasmen |
| Keywords: | Eurycoma longifolia Jack;Therapeutic dose;Hepatoprotective |
| Issue Date: | Apr-2013 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. Cl.8: A61K 36/00, A01D 7/54 |
| Abstract: | The hepatoprotective activity of Eurycoma longifolia Jack. roots methanol-water fraction on therapeutic dose was evaluated in carbon tetrachloride (CCl4)-induced rats. Hepatic cells were still normal after three months administration of methanol-water fraction at therapeutic dose. The administration of methanol-water fraction on therapeutic dose prior to CCl4-induced or CCl4-induced prior to methanol-water fraction resulted in suppression of ALT and AST. Histopathological and ultrastructure studies confirmed that methanol-water fraction protected hepatic cells. It is concluded that the methanol-water fraction of pasak bumi roots has a hepatoprotective activity. |
| Page(s): | 225-230 |
| ISSN: | 0975-1068 (Online); 0972-5938 (Print) |
| Appears in Collections: | IJTK Vol.12(2) [April 2013] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJTK 12(2) 225-230.pdf | 1.02 MB | Adobe PDF | View/Open |
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