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Title: Effect of Vanillin on lipid profile in a model of hyperlipidemia, a preliminary study
Authors: Belagali, Yogesh
Ullal, Sheetal D
Shoeb, Ahsan
Bhagwath, Vani
Ramya, K
Maskeri, Rakshitha
Keywords: Hypertriglyceridemia;Lipid profile;Vanillin
Issue Date: Apr-2013
Publisher: NISCAIR-CSIR, India
Abstract: To evaluate the effect of vanillin on the lipid profile of high fat diet induced hyperlipidemia in rats, the hyperlipidemia was induced by feeding cholesterol-rich high fat diet for 45 days in wistar rats of either sex. The reduction in the triglycerides and VLDL-C was significant at 200 & 400 mg/kg dose of vanillin compared to atorvastatin group. Reduction in total cholesterol was significant at 200 and 400 mg/kg doses compared to hyperlipidemic control. The results demonstrate that vanillin at a dose of 200 and 400 mg/kg body weight lowers the serum triglyceride, VLDL-C and total cholesterol level significantly in high fat diet induced hyperlipidemic rats. However there was no significant effect on the lipid profile at 100 mg/kg dose. There were no statistically significant changes in the HDL-C and LDL-C levels at any of the given doses.
Page(s): 288-291
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.51(04) [April 2013]

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