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dc.contributor.authorMandal, Arpita-
dc.contributor.authorPaul, Tanmay-
dc.contributor.authorRoy, Suchismita-
dc.contributor.authorMandal, Shreya-
dc.contributor.authorPradhan, Shrabani-
dc.contributor.authorMondal, Keshab Ch.-
dc.contributor.authorNandi, Dilip Kumar-
dc.identifier.issn0975-1009 (Online); 0019-5189 (Print)-
dc.description.abstractThe total antioxidative activity of L. ingluviei ADK10 isolated from chicken intestine intact cells and cell free culture supernatant (CFCS) was 54- 67.95%. The ability to scavenge a,a-Diphenyl-b-Picrylhydrazyl free radical ranged from 71 and 64% in intact cells and CFCS respectively. Total reducing activity of bacteria was equivalent to 290 µM/L of cysteine. Reducing glutathione activity was equivalent to 93.95µg/mL. Oral administration of the strain at a dose of 109 cfu/kg body weight to acetaminophen induced oxidative stress in rats increased catalase, glutathione and superoxide dismutase activity in the blood, liver and kidney and lowered malondialdehyde level. The results indicate that L. ingluviei ADK10 has potential free radical scavenging activity for the treatment of oxidative stress related disease. en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJEB Vol.51(02) [February 2013]en_US
dc.subjectFree radical scavenging activityen_US
dc.subjectLactobacillus ingluviei ADK10en_US
dc.subjectOxidative stressen_US
dc.titleEffect of newly isolated Lactobacillus ingluviei ADK10, from chicken intestinal tract on acetaminophen induced oxidative stress in Wistar ratsen_US
Appears in Collections:IJEB Vol.51(02) [February 2013]

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