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Title: Effect of high arsenic content in drinking water on rat brain
Authors: Chaudhuri, Aditi Nag
Basu, Srabanti
Chattopadhyay, Sukumar
Gupta, S Das
Issue Date: Feb-1999
Publisher: NISCAIR-CSIR, India
Abstract: The permissible limit of arsenic content in drinking water is 0.05 ppm, whereas, in many parts of West Bengal the arsenic level in drinking water is 0.1 ppm, frequently 0.3 ppm and even 3.0 ppm, though rarely. In order to assess possible risk to brain function by drinking such water, rats were given arsenic mixed in drinking water at the above four concentrations for 40 days. There was increased lipid peroxidation at all doses of arsenic, including the 'permissible limit', decrease in glutathione level, superoxide dismutase and glutathione reductase activities, indicating the free-radical-mediated degeneration of brain.
Page(s): 51-54
ISSN: 0975-0959 (Online); 0301-1208 (Print)
Appears in Collections:IJBB Vol.36(1) [February 1999]

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