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http://nopr.niscpr.res.in/handle/123456789/14361| Title: | Fuller’s earth catalyzed rapid synthesis of bis(indolyl)methanes under solvent free condition |
| Authors: | Kapuriya, Naval Kakadiya, Rajesh Savant, Mahesh M Pansuriya, Akshay M Bhuva, Chirag V Patel, Anil S Pipaliya, Piyush V Audichya, Vipul B Gangadharaiah, Sarala Anandalwar, Sridhar M Prasad, Javaregowda S Shah, Anamik Naliapara, Yogesh T |
| Keywords: | Fuller’s earth;Electrophilic addition;Bis(indolyl)¬methanes;Water mediated;Solvent free condition |
| Issue Date: | Jul-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A rapid and highly efficient synthesis of various bis(indolyl)methanes with high yield by the reaction of indoles 1a-c and arylaldehydes 2a'-m' in presence of fuller’s earth is demonstrated. This simple and versatile protocol is found to be an efficient catalyst for the electrophilic addition reaction of indole and works well under solvent free condition as well as in aqueous medium. The structure of newly synthesized compound 3m has been confirmed by single crystal X-ray crystallography. |
| Page(s): | 1032-1038 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.51B(07) [July 2012] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 51B(7) 1032-1038.pdf | 165.58 kB | Adobe PDF | View/Open |
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