Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/14358| Title: | Synthesis, characterization and antimicrobial screening of some quinoline based dihydropyridine and 2-oxo-azetidine derivatives |
| Authors: | Desai, N C Harsora, J P |
| Keywords: | Vilsmeier-Haack reaction;Quinoline;2-pyridone;Thiazole;Azetidinones |
| Issue Date: | Jul-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | 2-Chloro-8-methylquinoline-3-carbaldehyde 1 on treatment with 2-cyanoacetohydrazide and thiosemicarbazide yields schiff bases N'-((2-chloroquinolin-3-yl)methylene)-2-cyanoacetohydrazide 2 and 2-((2-chloro-8-methylquinolin-3-yl)methylene)hydrazinecarbothioamide 4, respectively. Compounds 2 and 4 have been used to obtain a series of titled compounds containing azetidinone, thiazole and 2-pyridone scaffolds incorporating quinoline nucleus. The newly synthesized compounds 3a-j and 6a-g have been screened for their antibacterial and antifungal activities and their chemical structures have been elucidated by spectral data. |
| Page(s): | 1011-1019 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.51B(07) [July 2012] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 51B(7) 1011-1019.pdf | 128.84 kB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.