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Title: | Synthesis, characterization and antimicrobial activity of some 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones |
Authors: | Desai, N C Bhatt, Nayan Kumar, Mukesh Makwana, Atul |
Keywords: | 2-Aminobenzoic acid;Benzene-1,2-diamine;Benzimidazole;Thiazolidinone;Antibacterial activity;Antifungal activity |
Issue Date: | Jul-2011 |
Publisher: | NISCAIR-CSIR, India |
Abstract: | As a part of systematic investigation of synthesis, characterization and biological activities, several new 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones 3a-l, have been synthesized from Schiff bases of benzimidazoles 2a-l, which have been prepared by condensation of different aldehydes with 2-(1H-benzo[d]imidazol-2-yl)benzenamine 1. Compound 1 was obtained by the reaction of 2-aminobenzoic acid and benzene-1,2-diamine. All the synthesized compounds have been evaluated for their antibacterial and antifungal activities against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Candida albicans, Asperigillus niger and Asperigillus clavatus. |
Page(s): | 941-945 |
ISSN: | 0975-0983(Online); 0376-4699(Print) |
Appears in Collections: | IJC-B Vol.50B(07) [July 2011] |
Files in This Item:
File | Description | Size | Format | |
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IJCB 50B(7) 941-945.pdf | 88.92 kB | Adobe PDF | View/Open |
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