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Title: | Antioxidant effect of Lagerstroemia speciosa Pers (Banaba) leaf extract in streptozotocin-induced diabetic mice |
Authors: | Saumya, S M Basha, P Mahaboob |
Keywords: | Diabetes;Free radicals;Lagerstroemia;Oxidative stress |
Issue Date: | Feb-2011 |
Publisher: | NISCAIR-CSIR, India |
Abstract: | Aqueous leaf extract of L. speciosa (banaba) effectively decreased the blood glucose in streptozotocin-induced diabetic mice after 15th day of banaba exposure. Further, banaba leaf extract have the potential to inhibit lipid peroxidation and effectively intercept/neutralize reactive oxygen species such as super oxide, H2O2 and NO based free radicals. The aqueous banaba leaf extract (150 mg/kg bodyweight) duly reduced STZ generated reactive intermediates and radical species helping to regulate normal levels of antioxidative markers like superoxide dismutase, catalase, glutathione- S-transferase and reduced glutathione. |
Page(s): | 125-131 |
ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
Appears in Collections: | IJEB Vol.49(02) [February 2011] |
Files in This Item:
File | Description | Size | Format | |
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IJEB 49(2) 125-131.pdf | 157.86 kB | Adobe PDF | View/Open |
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