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Title: Anti-inflammatory and antinociceptive activity of Justicia gendarussa Burm. f. leaves
Authors: Shikha, P
Latha, PG
Suja, SR
Anuja, G I
Shyamal, S
Shine, VJ
Sini, S
Krishna Kumar, N M
Rajasekharan, S
Keywords: Justicia gendarussa;Anti-inflammatory;Analgesic;Indomethacin;Acetyl salicylic acid
Issue Date: Dec-2010
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl.8A61 K 36/00, A61P 29/00
Abstract: The ethanolic extract of Justicia gendarussa Burm.f. leaves was screened for its anti-inflammatory and antinociceptive activity in experimental animals. The extract showed significant inhibition of carrageenan and formalin-induced paw oedema and cotton pellet-induced granuloma formation compared to the standard anti-inflammatory drug, Indomethacin. The extract at 125, 250 and 500 mg/kg showed significant inhibition of pain in the acetic acid-induced writhing and hot plate models in mice when compared to the standard analgesic drug, acetyl salicylic acid
Page(s): 456-461
ISSN: 0975-1033 (Online); 0379-5136 (Print)
Appears in Collections:IJNPR Vol.1(4) [December 2010]

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