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Title: Anti-inflammatory and analgesic activity of Barringtonia racemosa Roxb. fruits
Authors: Shikha, P
Latha, P G
Suja, S R
Anuja, G I
Shyamal, S
Shine, V J
Sini, S
Krishnakumar, N M
Rajasekharan, S
Keywords: Barringtonia racemosa;Anti-inflammatory;Analgesic;Indomethacin;Acetyl salicylic acid
Issue Date: Sep-2010
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl.8—A61K 36/00, A61P 29/00
Abstract: The ethanolic extract of Barringtonia racemosa Roxb. (Lecythidaceae) fruits were screened for its anti-inflammatory and analgesic effects in experimental animals. The extract showed significant inhibition of carrageenan/formalin induced paw oedema at the three doses used in the study. The activity of the extract was comparable to that of Indomethacin, the standard anti-inflammatory drug. B. racemosa ethanolic extract also showed significant inhibition of acetic acid induced writhing in mice at 125, 250 and 500 mg/kg doses almost comparable to the standard analgesic drug, acetyl salicylic acid.
Page(s): 356-361
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.1(3) [September 2010]

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