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Title: | Synthesis of some biologically important fluorinated 3-chlorochromones and 1,5-benzothiazepines as antimicrobial and antifungal agents |
Authors: | Ghotekar, D S Joshi, R S Mandhane, P G Bhagat, S S Gill, C H |
Keywords: | Chalcones;3-chlorochromones;1,5-benzo¬thia¬zepines;antimicrobial;antifungal agents |
Issue Date: | Sep-2010 |
Publisher: | CSIR |
Abstract: | A series of synthetic 3-chlorochromones and 1,5-benzothiazepines have been synthesized and evaluated for their antimicrobial and antifungal activity against Gram +ve and Gram -ve microorganisms. In these series the chemical transformation of chalcones to respective 3-chlorochromones and 1,5-benzothiazepines by using DMSO/CuCl2 and 2-aminothiophenol respectively has been carried out. Compounds synthesized have been screened for antibacterial activity using Gentamycin and Cefixime and for antifungal activity using Ketoconazole as reference drugs. |
Page(s): | 1267-1270 |
ISSN: | 0975-0983(Online); 0376-4699(Print) |
Appears in Collections: | IJC-B Vol.49B(09) [September 2010] |
Files in This Item:
File | Description | Size | Format | |
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IJCB 49B(9) 1267-1270.pdf | 73.86 kB | Adobe PDF | View/Open |
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