Spectral editing with 2D E-HMQC NMR spectroscopy for CD<i style="">_n</i> groups: A theoretical study

Abstract

In order to get the simplified spectra for separation of carbonyl groups, the spectral editing of NMR signals has become a useful technique for complex molecules. E-HMQC is a ¹H-dedected, edited-pulse angle and two-dimensional NMR experiment which allows the selective detection of CH, CH₂ and CH₃ signals. The product operator theory is widely used for analytical description of the spectral editing NMR experiments for weakly coupled spin systems. In the present study, analytical descriptions of the 2D ²H-dedected E-HMQC NMR experiment have been presented for weakly coupled <i style="">IS_n</i> (<i style="">I</i>=½; <i style="">S</i>=1; <i style="">n</i>=1, 2, 3) spin systems by using the product operator theory. By using obtained FID values, theoretical discussion and experimental suggestions for sub-spectral editing of CD, CD₂ and CD₃ groups have been made.