Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/9933
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dc.contributor.authorAsundaria, Shahrukh T-
dc.contributor.authorPatel, Keshav C-
dc.date.accessioned2010-07-09T11:13:25Z-
dc.date.available2010-07-09T11:13:25Z-
dc.date.issued2010-07-
dc.identifier.urihttp://hdl.handle.net/123456789/9933-
dc.description960-964en_US
dc.description.abstract4-Sulfonamide substituted novel sydnones have been synthesized. The synthetic strategy utilizes 4,4′-diamino­diphenyl­sulfone as starting material to obtain the 3,3′-(sulfonyldi-4,1-phenylene)bis(4-chlorosulfonyl)sydnone 6 through several steps viz. esterification, hydrolysis (saponification), nitrosation, cyclisa­tion and chlorosulfonation, which are then condensed with different secondary amines to get final compounds. All new compounds have been characterized by spectral data as well as elemental analysis and have been tested for their antibacterial activity against gram positive S. pneumoniae and S. aureus, and gram negative bacteria E. coli and P. aeruginosa. Some of the synthesized compounds show excellent antimicrobial activity.en_US
dc.language.isoen_USen_US
dc.publisherCSIRen_US
dc.sourceIJC-B Vol.49B(07) [July 2010]en_US
dc.subjectSynthesisen_US
dc.subjectbis-sydnoneen_US
dc.subjectin vitroen_US
dc.subjectmesoionicen_US
dc.subjectpharmacologicalen_US
dc.titleSynthesis and characterization of some sulfonamide based bis-sydnones and their in vitro antimicrobial activityen_US
dc.typeArticleen_US
Appears in Collections:IJC-B Vol.49B(07) [July 2010]

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