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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(07) [July 2010] >
| Title: | Synthesis, antimicrobial and insecticidal activity of some 4H-1,2,4 triazole derivatives |
| Authors: | Gautam, Nidhi
Chourasia, O P |
| Keywords: | 4H-1
2,4 Triazole
antibacterial activity
antifungal activity and insecticidal activity |
| Issue Date: | Jul-2010 |
| Publisher: | CSIR |
| Abstract: |
1-(Substituted
benzylidene) semicarbazide has been used as a precursor to synthesize some
important biologically active 3-substituted phenyl, 4H-1,2,4 triazole derivatives. Reaction of ethanolic solution of
schiff's base of substituted aromatic aldehyde 1 with ethanolic solution of FeCl3.6H2O (1
mole FeCl3.6H2O in 10 mL ethanol) yields the 4H-1,2,4 triazole-3-derivative 2. Several derivatives have been
synthesized and screened for their antibacterial efficacy against Bacillus subtilis, Escherichia coli, Staphyllococcus
aureus and Klebsiella pneumoniae,
Antifungal activity against Aspergillus flavus, Fusarium
oxysporum, Aspergillus niger and Trichoderma viridae and insecticidal activity
against Periplaneta americana.
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| Page(s): | 956-959 |
| Source: | IJC-B Vol.49B(07) [July 2010]
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