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dc.contributor.authorBhattacharjee, Soumen-
dc.identifier.issn0975-0967 (Online); 0972-5849 (Print)-
dc.description.abstractPolyomaviruses (PyVs), members of the family Polyomaviridae, are strictly vertebrate resident viruses implicated in various pathogenic conditions including neoplasias, especially in human. This study aims to review both nucleotide and amino acid sequences of large T-antigen (LTAg), virion protein 1 (VP1) gene and also whole genomes of all known PyVs till date, in ascertaining phylogenetic relationships among themselves. The study detected genomic recombinations within the oncoprotein LTAg coding sequences of PyV group, and identified unique nucleotide and amino acid positions in the conserved regions of PyV-LTAg coding sequence, which can facilitate strain differentiations in clinical samples.en_US
dc.sourceIJBT Vol.9(3) [July 2010]en_US
dc.subjectLarge T-antigen (LTAg)en_US
dc.subjectviral protein 1 (VP1)en_US
dc.titleEvolutionary interrelationships among polyomaviruses based on nucleotide and amino acid variationsen_US
Appears in Collections:IJBT Vol.09(3) [July 2010]

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